Questions assessing basic science concepts are covered on Step 1. However, foundational science knowledge will often be needed to answer items on Step 2 CK, even if the question is focused on diagnosis or management. You can see examples of Step 2 CK items that require foundational science knowledge here.
These examples include an explanation of why and how foundational science is needed to answer a test item that is not primarily focused on basic science. Foundational science knowledge is needed both for licensure examinations and for lifelong learning that continues beyond assessment.